Hydroxypropyl methylcellulose (HPMC) ndi ether yomwe imagwiritsidwa ntchito kwambiri pa cellulose yomwe imadziwika chifukwa cha kukhuthala kwake.Amagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana, kuphatikizapo zomangamanga, mankhwala, chakudya ndi chisamaliro chaumwini.Mu pepala ili, timayang'ana kwambiri za kukhuthala kwa HPMC ndikuwunika zomwe zimayambitsa kukhuthala kwake.
Njira yowonjezereka ya HPMC ndi:
Kukula kwa HPMC kumatheka chifukwa cha mawonekedwe ake apadera a maselo.Molekyu ya HPMC imakhala ndi msana wa maunyolo a cellulose okhala ndi hydroxypropyl ndi magulu a methyl ophatikizidwa.Pamene HPMC imamwazikana m'madzi kapena zosungunulira zina, maunyolo a cellulose amayamwa madzi ndikutupa, zomwe zimapangitsa kuti pakhale mawonekedwe a 3D network.Netiweki iyi imatseketsa zosungunulira ndikuwonjezera kukhuthala kapena kubalalitsidwa kwa yankho.
Zinthu zomwe zimakhudza mphamvu ya thickening:
Kuyikira Kwambiri: Kuchuluka kwa HPMC mu kapangidwe kake kumatenga gawo lalikulu pakukulitsa kwake.Kuchulukirachulukira kumachulukirachulukira, mamolekyu ambiri a HPMC amalumikizana, zomwe zimapangitsa kukhuthala komanso kukhuthala.
Kulemera kwa mamolekyu: Kulemera kwa maselo a HPMC kumakhudza kukhuthala kwake.HPMC yolemera kwambiri ya mamolekyu nthawi zambiri imakhala yolimba kwambiri poyerekeza ndi magiredi ocheperako.
Kutentha: Kutentha kungakhudze khalidwe lokulitsa la HPMC.
PH: PH ya yankho imatha kukhudzanso kukhuthala kwa HPMC. Makalasi ena a HPMC amatha kuwonetsa kukhuthala bwino pamitundu inayake ya pH, pomwe ena amatha kukhala okhudzidwa kwambiri ndi kusintha kwa pH.
Shear Rate: Kumeta ubweya wa ubweya, kapena mlingo umene njira yothetsera vutoli imakhudzidwa ndi kupanikizika kwa makina, ingakhudze khalidwe lokulitsa la HPMC. mitengo ya kukameta ubweya, monga pa kusonkhezera kapena ntchito, mamasukidwe akayendedwe akhoza kuchepa chifukwa kukameta ubweya kuswa dongosolo lopangidwa ndi HPMC.
Ntchito za Thickened HPMC:
Kukhuthala kwa HPMC kumapangitsa kukhala chowonjezera chofunikira pamapulogalamu ambiri.Ntchito zina zodziwika bwino ndi izi:
Zomangamanga: HPMC imagwiritsidwa ntchito muzinthu zomata monga matope ndi zomatira matailosi kuti zithandizire kugwirira ntchito kwawo, kusunga madzi komanso kukana kwamadzi.
Mankhwala: HPMC imagwiritsidwa ntchito ngati chowonjezera pa kuyimitsidwa kwapakamwa, njira za ophthalmic ndi ma gels apamutu, kupereka kusasinthika komwe kumafunidwa komanso kupititsa patsogolo kaperekedwe ka mankhwala.
Chakudya & Chakumwa: HPMC imagwiritsidwa ntchito pazinthu zosiyanasiyana zazakudya monga sosi, mavalidwe ndi zokometsera kuti zikhazikike, kukhazikika komanso kumva pakamwa.
Kusamalira Munthu Payekha ndi Zodzoladzola: HPMC imapeza ntchito muzinthu zosamalira anthu, kuphatikiza mafuta odzola, mafuta odzola ndi opangira tsitsi, monga chowonjezera, chokhazikika komanso chopangira mafilimu.
Hydroxypropyl methylcellulose (HPMC) imawonetsa kukhuthala kwakukulu chifukwa cha mawonekedwe ake apadera a maselo komanso kulumikizana ndi madzi.Kumvetsetsa zinthu zomwe zimakhudza kukula kwa HPMC, monga kukhazikika, kulemera kwa maselo, kutentha, pH, ndi kumeta ubweya wa ubweya, n'kofunika kwambiri popanga zinthu zokhala ndi kukhuthala kofunikira komanso kusasinthasintha. mafakitale osiyanasiyana, opereka magwiridwe antchito opitilira muyeso komanso mawonekedwe abwino azinthu.
